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GlyCanTargeters - Engineering Glycan Targeters for Precise Recognition in Colorectal Cancer Diagnostics and Modulation of Microbiome-Cancer Cell Interactions announces the opening of a call for one Research Fellowship for a Master’s degree holder.
The fellowship will be developed under the scientific supervision of Benedita Andrade
Pinheiro (Principal Investigator), in close collaboration with Prof. Maria Angelina de Sá Palma
and Dr. Ana Luísa Moreira de Carvalho, integrating the Functional Glycobiology (GlycoLab) and
Macromolecular Crystallography (Xtal) laboratories. The work will be carried out at UCIBIO labs in the Department of Chemistry, NOVA School of Science and Technology, Caparica Campus. The selected candidate will join an interdisciplinary and internationally connected research team. Mobility periods in partner laboratories are foreseen and covered within the project framework.The GlyCanTargeters project aims to engineer O-glycan-binding modules derived from human microbiome bacteria to specifically recognise aberrant mucin-type O-glycosylation patterns in colorectal cancer (CRC). The project combines structural biology, protein engineering, glycan microarray technology, biophysical characterisation (ITC, MST) and CRC cell line validation
The selected candidate will contribute to the development of next-generation glycan-targeting tools with potential applications in CRC diagnostics and microbiome modulation.This fellowship offers an excellent opportunity for a recent Master’s graduate to contribute to a cutting-edge project in structural glycobiology and cancer research, gain advanced training in protein engineering and glycan technologies, work within a strong national and international, collaborative network, and develop skills supporting an academic or translational research career.
For further information about the scientific aspects of the project, interested candidates may contact:
Dr. Benedita Andrade Pinheiro (b.pinheiro@fct.unl.pt)